Akkermansia muciniphila · Symptoms & clinical context

Read condition-specific symptoms and clinical context for Akkermansia muciniphila. A mucus-layer specialist that lives on mucin and is present in most healthy adults.

About this organism

A. muciniphila lives in the intestinal mucus layer and uses mucin as its carbon and nitrogen source. Reviews put it at 1 to 3% of the faecal microbiota and present in more than 90% of healthy adults tested, rising from 16% of samples at one month of age to 90% by twelve months and decreasing in the elderly. It is a Gram-negative, non-motile, non-spore-forming oval cell that tolerates oxygen for up to 72 hours despite being an anaerobe. Lower abundance has been reported alongside obesity, type 2 diabetes, inflammatory and liver diseases, and small human trials of pasteurized preparations report metabolic effects; these remain exploratory findings rather than established treatments.

Resident context

This profile describes a normal resident of the intestinal mucus layer, not an infection. No symptoms are listed and none are invented. Reviews report lower abundance alongside obesity, type 2 diabetes, inflammatory diseases, liver diseases and cancer; those are associations with conditions that have many causes, not symptoms caused by this bacterium. Reported improvements in glucose tolerance and insulin sensitivity come from mouse studies and small human cohorts and are not established treatments.

Profile sources

Source check: 2026-09-19. Educational content; independent scientific review remains pending.

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